Stress
There are the day-to-day stresses of dealing with demanding clients and the sometimes fruitless attempts to communicate the vision to your designers, but you can't really complain. You get to exercise your creative muscles, hang out with your best friends (computers) all day, and take home a nice paycheck.
The only real cause of stress in your life comes from worrying that your wife will find out it was you who backed over her azaleas.